Tuesday, 29th August The Joint Annual Scientific Meetings of the Endocrine Society of Australia and the Society for Reproductive Biology 2017

The conference acknowledges the support of

• Premature ovarian insufficiency  - Gerard Conway

The conference acknowledges the support of

• Stimulating the ageing ovary: time for a new approach? - Mark Green

The conference acknowledges the support of

• Etoposide results in follicle loss in the fetal mouse ovary, but does not block the ability of oocytes to progress through prophase I of meiosis - Agnes Stefansdottir

The conference acknowledges the support of

• Engineering TGF-β proteins for the diagnosis and treatment of reproductive disorders - Kelly L Walton
• Control of energy homeostasis and metabolism: implications for oocyte quality and reproductive potential - Michael J Bertoldo
• Mitochondrial permeability transition pore formation during chilling and cryopreservation of stallion spermatozoa - Zamira Gibb

10:00 AM Cherie Chiang
HEDT (harmonised endocrine dynamic testing) and adaptation into local practice: endocrine and pathology department prospectives

Controversial tests: public forum discussion. Panel of HEDT working group

10:15 AM Warrick Inder
Water deprivation test

10:34 AM Penelope Coates
72 hr fast

10:53 AM Mathis Grossmann
TRH and tertroxin suppression test

11:08 AM Cherie Chiang
N saline suppresion test and AVS

11:27 AM Ee Mun Lim
Cushing

11:46 AM Warrick Inder
Conclusion, and future directions

• The relative roles of adipose and skeletal muscle thermogenesis in determining weight loss and weight gain; studies from a large animal model - Belinda A Henry
• Colder, browner and thinner? - Jenny Gunton
• Diet-induced thermogenesis: fake friend or foe - Ken Ho

The conference acknowledges the support of

• Advanced parental age is associated with decreased gamete quality and altered early embryonic development. - Macarena Gonzalez
• The lipid peroxidation product 4-hydroxynonenal contributes to oxidative stress-mediated deterioration of the ageing oocyte - Bettina P Mihalas
• Maternal obesity alters the levels of Ten-Eleven Translocase (TET) proteins reducing 5-methylcytosine and 5-hydroxymethylcytosine in the early embryo - Alexander Penn
• Characterisation of a novel role for the dynamin mechanoenzymes in the regulation of human sperm acrosomal exocytosis - Wei Zhou

• BMP15 mutations associated with female reproductive disorders reduce expression, activity, or synergy with GDF9. - William A Stocker
• Phrophylactic immunostimulation attenuates the adverse effects of Influenza infection during pregnancy - Jeff Lauzon-Joset
• IFNG perturbs TGFB-mediated induction of CSF2 during the female ectocervical immune response to seminal fluid - David J Sharkey
• RNA-sequencing reveals seminal fluid regulation of T cell receptor signalling pathway genes in the peri-implantation phase endometrium in mice - Hon Y Chan

Chairs: Lisa Akison, Michael Bertoldo (SRB), Tim Cole, Belinda Henry (ESA)
Lunch boxes will be served directly outside the room. Please grab one on your way in.

12:30pm Brief introduction and welcome by the ECR chairs (Lisa Akison)

12:32-1:10pm Panel Discussion: ‘Navigating the transition from Post-doc to independent scientist’

12:32-12:57pm 5 min presentations by each panel member
A/Prof Wendy Ingman (University of Adelaide)
Dr Karla Hutt (Monash University)
Dr Jeremy Smith (University of Western Australia)
Dr Renea Taylor (Monash University)
Dr Kevin Pfleger (University of Western Australia)

12:57-1:10pm Open Discussion with questions from ECR members (including via Twitter)

1:10-1:25pm ‘Benchmarking’ session on building a competitive CV for grants/fellowships.
What are the most important elements to concentrate on?
Presented by A/Prof Rob Gilchrist (University of NSW)

1:25-1:30pm Close

The conference acknowledges the support of

• Effect of mineralocorticoid blockade on human brown fat – a randomised placebo-controlled cross-over study - Moe Thuzar
• Effects of central sympathoinhibition with moxonidine on the elevated sympathetic nervous activity and downstream metabolic abnormalities observed in polycystic ovary syndrome – a double blind randomised controlled trial - Soulmaz Shorakae
• Non-vertebral fractures are associated with higher sex hormone binding globulin levels in men receiving dialysis pre-transplantation. - Jasna Aleksova
• Relative hyperglycaemia is an independent predictor of mortality in the critically ill patient - Tien F Lee
• Circulating advanced glycation end products and their endogenous secretory receptor are associated with bone turnover markers and with incidence of hip fracture in older men - Lydia Lamb
• Development of a next generation sequencing platform for comprehensive somatic mutation testing in thyroid cancer - Michael Mond

• Endometrial mesenchymal stromal/stem cells modulate the macrophage response to implanted polyamide/gelatin composite mesh in immunocompromised and immunocompetent mice - Caroline Gargett
• Immune privilege and neoplasia in human testis: potential role and functional polarization of M1 and M2 macrophages and dendritic cells - Dana Pueschl
• N-cadherin identifies human endometrial epithelial progenitor cells - Caroline E Gargett

The conference acknowledges the support of

• Managing osteoporosis in underserved populations - Frances Milat

The conference acknowledges the support of

• Deciphering the molecular mechanisms underlying oocyte apoptosis during chemotherapy - Quynh-Nhu Nguyen
• The targeted disruption of lipoxygenase enzymes prevents oxidative stress in the male germline - Elizabeth Bromfield
• The role of the (Pro)renin receptor in trophoblast proliferation, migration and invasion - Samantha L Rodrigues
• Periconceptional alcohol exposure in the rat causes sex-specific changes to pre-implantation development and trophoblast differentiation - Jacinta I Kalisch-Smith